American Academy of Ophthalmology, Robert H. Rosa Jr. MD's 2014-2015 Basic and Clinical Science Course (BCSC): Section PDF

By American Academy of Ophthalmology, Robert H. Rosa Jr. MD

Part four offers fabrics in components: half I, Ophthalmic Pathology; and half II, Intraocular Tumors: scientific points. half I makes use of a hierarchy that strikes from normal to precise to assist derive a differential analysis for a selected tissue. half II is a compilation of chosen scientific facets of significance to the final ophthalmologist. Following half II are the yank Joint Committee on melanoma 2010 staging varieties for ocular and adnexal tumors.

Upon crowning glory of part four, readers might be capable to:

Describe a based method of figuring out significant ocular stipulations in response to a hierarchical framework of topography, disorder method, common analysis and differential diagnosis
Summarize the stairs in dealing with ocular specimens for pathologic examine, together with acquiring, dissecting, processing, and marking tissues
Identify these ophthalmic lesions that point out systemic ailment and are possibly existence threatening

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Extra resources for 2014-2015 Basic and Clinical Science Course (BCSC): Section 4: Ophthalmic Pathology and Intraocular Tumors

Example text

Whether the patient is age 4 or age 44 makes a tremendous difference in interpretation. Orientation Globes may be oriented according to the location of the extraocular muscles and of the long posterior ciliary arteries and nerves, which are located in the horizontal meridian. The medial, inferior, lateral, and superior rectus muscles insert progressively farther from the limbus. Locating the insertion of the inferior oblique muscle is very helpful in distinguishing between a right and a left eye (Fig 3-1).

CHAPTER . 3 ------------~-------------- Specimen Handling Communication Communication with the pathologist before, during, and after surgical procedures is an essential aspect of quality patient care. org). The final histologic diagnosis reflects successful collaborative work between clinician and pathologist. The ophthalmologist should provide a relevant and reasonably detailed clinical history when the specimen is submitted to the laboratory. This history facilitates clinicopathologic correlation and enables the pathologist to provide the most accurate interpretation of the specimen.

3d Microarray-based CGH (array CGH) th Advantages Disadvantages Quality snap-frozen tissue (optimal) and archival paraffinembedded tissue 1. Variable success rate of RNA extraction 2. Contamin ation with other nucleic acid material Variable success rate of RNA extraction Direct detection of PCR-product formation by measuring the increase in fluorescent emission continuously during the PCR reaction 1. Detects and maps alterations in copy number of DNA sequences 2. Analyzes all chromosomes in a single experiment and no dividing cells required High resolution Inability to detect mosaicism, balanced chromosomal translocations, inversions, and whole-genome ploidy ch anges 1.

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